Ontology highlight
ABSTRACT:
SUBMITTER: Zhou H
PROVIDER: S-EPMC7105744 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhou He H Sun Lin L Zhang Siwen S Zhao Xue X Gang Xiaokun X Wang Guixia G
Frontiers in endocrinology 20200324
Type 1 diabetes (T1D) is a multifactorial autoimmune disease mediated by genetic, epigenetic, and environmental factors. In recent years, the emergence of high-throughput sequencing has allowed us to investigate the role of gut microbiota in the development of T1D. Significant changes in the composition of gut microbiome, also termed dysbiosis, have been found in subjects with clinical or preclinical T1D. However, whether the dysbiosis is a cause or an effect of the disease remains unclear. Curr ...[more]