Ontology highlight
ABSTRACT:
SUBMITTER: Tian L
PROVIDER: S-EPMC7106036 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Tian Lin L Shen Xuejuan X Murphy Robert W RW Shen Yongyi Y
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20180602
Viruses depend on their host's cellular structure to survive. Most of them do not have tRNAs, their translation relies on hosts' tRNA pools. Over the course of evolution, viruses needed to optimally exploit cellular processes of their host. Thus, codon usage of a virus should coevolve with its host to efficiently and rapidly replicate. Some viruses can invade a broad spectrum of hosts (BSTVs), while others can invade a narrow spectrum only (NSTVs). Consequently, we test the hypothesis that simil ...[more]