Ontology highlight
ABSTRACT:
SUBMITTER: Guo Q
PROVIDER: S-EPMC7106735 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Guo Qingguo Q Zhang Tianrui T Meng Na N Duan Yuran Y Meng Yuan Y Sun Dong D Liu Ying Y Luo Guangzuo G
Cell & bioscience 20200330
<h4>Background</h4>Exocytosis is a process by which vesicles are transported to and fused with specific areas of the plasma membrane. Although several studies have shown that sphingolipids are the main components of exocytic compartments, whether they control exocytosis process is unclear.<h4>Results</h4>Here, we have investigated the role of sphingolipids in exocytosis by reducing the activity of the serine palmitoyl-transferase (SPT), which catalyzes the first step in sphingolipid synthesis in ...[more]