Ontology highlight
ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC7111670 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Zhang Weidong W Bouwman Kim M KM van Beurden Steven J SJ Ordonez Soledad R SR van Eijk Martin M Haagsman Henk P HP Verheije M Hélène MH Veldhuizen Edwin J A EJA
Virology 20170704
Mannose binding lectin (MBL) is a collagenous C-type lectin, which plays an important role in innate immunity. It can bind to carbohydrates on the surface of a wide range of pathogens, including viruses. Here we studied the antiviral effect of recombinant chicken (rc)MBL against Infectious Bronchitis Virus (IBV), a highly contagious coronavirus of chicken. rcMBL inhibited in a dose-dependent manner the infection of BHK-21 cells by IBV-Beaudette, as detected by immunofluorescence staining of vira ...[more]