Ontology highlight
ABSTRACT:
SUBMITTER: Choteau L
PROVIDER: S-EPMC4940739 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Choteau Laura L Vasseur Francis F Lepretre Frederic F Figeac Martin M Gower-Rousseau Corine C Dubuquoy Laurent L Poulain Daniel D Colombel Jean-Frederic JF Sendid Boualem B Jawhara Samir S
Scientific reports 20160712
Mannose-binding lectin, together with mannose-associated serine proteases, activates the lectin pathway of the complement system and subsequent inflammatory mechanisms. An association between mannose-binding lectin deficiency and anti-Saccharomyces cerevisiae antibody levels is observed in Crohn's disease and this deficiency is frequently associated with a severe Crohn's disease phenotype. In the present study, we assessed the relationship between serum concentrations of mannose-binding lectin, ...[more]