Emergence of a group 3 coronavirus through recombination.
Ontology highlight
ABSTRACT:
SUBMITTER: Jackwood MW
PROVIDER: S-EPMC7111905 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Publications
Emergence of a group 3 coronavirus through recombination.
Jackwood Mark W MW Boynton Tye O TO Hilt Deborah A DA McKinley Enid T ET Kissinger Jessica C JC Paterson Andrew H AH Robertson Jon J Lemke Conelia C McCall Amber W AW Williams Susan M SM Jackwood Joshua W JW Byrd Lauren A LA
Virology 20100301 1
Analyses of turkey coronavirus (TCoV), an enteric disease virus that is highly similar to infectious bronchitis virus (IBV) an upper-respiratory tract disease virus in chickens, were conducted to determine the adaptive potential, and genetic changes associated with emergence of this group 3 coronavirus. Strains of TCoV that were pathogenic in poults and nonpathogenic in chickens did not adapt to cause disease in chickens. Comparative genomics revealed two recombination sites that replaced the sp ...[more]
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