"Breathing" Hemagglutinin Reveals Cryptic Epitopes for Universal Influenza Vaccine Design.
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ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC7112349 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
"Breathing" Hemagglutinin Reveals Cryptic Epitopes for Universal Influenza Vaccine Design.
Cell 20190501 5
A universal vaccine against influenza remains a critical target, and efforts have recently focused on the stem of the hemagglutinin glycoprotein. In this issue of Cell and a related Cell Host & Microbe article, three studies identify broad protective epitopes in the hemagglutinin head domain that are exposed by trimer "breathing." ...[more]
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