Dataset Information

The impact of ambient fine particles on influenza transmission and the modification effects of temperature in China: A multi-city study.

ABSTRACT:

Background

There is good evidence that air pollution is a risk factor for adverse respiratory and vascular health outcomes. However, data are limited as to whether ambient fine particles contribute to the transmission of influenza and if so, how the association is modified by weather conditions.

Objectives

We examined the relationship between ambient PM_2.5 and influenza incidence at the national level in China and explored the associations at different temperatures.

Methods

Daily data on concentrations of particulate matter with aerodynamic diameter<2.5?m (PM_2.5) and influenza incidence counts were collected in 47 Chinese cities. A Poisson regression model was used to estimate the city-specific PM_2.5-influenza association, after controlling for potential confounders. Then, a random-effect meta-analysis was used to pool the effects at national level. In addition, stratified analyses were performed to examine modification effects of ambient temperature.

Results

For single lag models, the highest effect of ambient PM_2.5 on influenza incidence appeared at lag day 2, with relative risk (RR) of 1.015 (95% confidence interval (CI): 1.004, 1.025) associated with a 10?g/m³ increase in PM_2.5. For moving average lag models, the significant association was found at lag 2-3days, with RR of 1.020 (95% CI: 1.006, 1.034). The RR of influenza transmission associated with PM_2.5 was higher for cold compared with hot days. Overall, 10.7% of incident influenza cases may result from exposure to ambient PM_2.5.

Conclusions

Ambient PM_2.5 may increase the risk of exposure to influenza in China especially on cooler days. Control measures to reduce PM_2.5 concentrations could potentially also be of benefit in lowering the risk of exposure and subsequent transmission of influenza in China.

SUBMITTER: Chen G

PROVIDER: S-EPMC7112570 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Publications

The impact of ambient fine particles on influenza transmission and the modification effects of temperature in China: A multi-city study.

Chen Gongbo G Zhang Wenyi W Li Shanshan S Zhang Yongming Y Williams Gail G Huxley Rachel R Ren Hongyan H Cao Wei W Guo Yuming Y

Environment international 20161011

<h4>Background</h4>There is good evidence that air pollution is a risk factor for adverse respiratory and vascular health outcomes. However, data are limited as to whether ambient fine particles contribute to the transmission of influenza and if so, how the association is modified by weather conditions.<h4>Objectives</h4>We examined the relationship between ambient PM<sub>2.5</sub> and influenza incidence at the national level in China and explored the associations at different temperatures.<h4> ...[more]

PMID: 27745688

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Project description:BackgroundPrevious literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations.ObjectivesWe examined the short-term temperature-suicide relationship using daily time-series data collected for 341 locations in 12 countries for periods ranging from 4 to 40 y.MethodsWe conducted a two-stage meta-analysis. First, we performed location-specific time-stratified case-crossover analyses to examine the temperature-suicide association for each location. Then, we used a multivariate meta-regression to combine the location-specific lag-cumulative nonlinear associations across all locations and by country.ResultsA total of 1,320,148 suicides were included in this study. Higher ambient temperature was associated with an increased risk of suicide in general, and we observed a nonlinear association (inverted J-shaped curve) with the highest risk at 27°C. The relative risk (RR) for the highest risk was 1.33 (95% CI: 1.30, 1.36) compared with the risk at the first percentile. Country-specific results showed that the nonlinear associations were more obvious in northeast Asia (Japan, South Korea, and Taiwan). The temperature with the highest risk of suicide ranged from the 87th to 88th percentiles in the northeast Asian countries, whereas this value was the 99th percentile in Western countries (Canada, Spain, Switzerland, the UK, and the United States) and South Africa, where nearly linear associations were estimated. The country-specific RRs ranged from 1.31 (95% CI: 1.19, 1.44) in the United States to 1.65 (95% CI: 1.40, 1.93) in Taiwan, excluding countries where the results were substantially uncertain.DiscussionOur findings showed that the risk of suicide increased with increasing ambient temperature in many countries, but to varying extents and not necessarily linearly. This temperature-suicide association should be interpreted cautiously, and further evidence of the relationship and modifying factors is needed. https://doi.org/10.1289/EHP4898.

Dataset Information

The impact of ambient fine particles on influenza transmission and the modification effects of temperature in China: A multi-city study.

Background

Objectives

Methods

Results

Conclusions

Publications

The impact of ambient fine particles on influenza transmission and the modification effects of temperature in China: A multi-city study.

Similar Datasets

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