Ontology highlight
ABSTRACT:
SUBMITTER: Gubbins MJ
PROVIDER: S-EPMC7112650 | biostudies-literature | 2005 Jan
REPOSITORIES: biostudies-literature
Gubbins Michael J MJ Plummer Frank A FA Yuan Xin Y XY Johnstone Darrell D Drebot Mike M Andonova Maya M Andonov Anton A Berry Jody D JD
Molecular immunology 20050101 1
The availability of monoclonal antibodies (mAbs) specific for the SARS-coronavirus (SARS-CoV) is important for the development of both diagnostic tools and treatment of infection. A molecular characterization of nine monoclonal antibodies raised in immune mice, using highly purified, inactivated SARS-CoV as the inoculating antigen, is presented in this report. These antibodies are specific for numerous viral protein targets, and six of them are able to effectively neutralize SARS-CoV in vitro, i ...[more]