Ontology highlight
ABSTRACT:
SUBMITTER: Haddad R
PROVIDER: S-EPMC7112899 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Haddad Rodrigo R Kashima Simone S Rodrigues Evandra Strazza ES Azevedo Rochele R Palma Patrícia Vianna Bonini PV de Magalhães Danielle Aparecida Rosa DA Zago Marco Antonio MA Covas Dimas Tadeu DT
Journal of virological methods 20110126 1
Since the discovery of RNAi technology, several functional genomic and disease therapy studies have been conducted using this technique in the field of oncology and virology. RNAi-based antiviral therapies are being studied for the treatment of retroviruses such as HIV-1. These studies include the silencing of regulatory, infectivity and structural genes. The HTLV-1 structural genes are responsible for the synthesis of proteins involved in the entry, assembly and release of particles during vira ...[more]