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Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts.

ABSTRACT: A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.

SUBMITTER: Lazreg F

PROVIDER: S-EPMC7113546 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Aerobic synthesis of <i>N</i>-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts.

Lazreg Faïma F Vasseur Marie M Slawin Alexandra M Z AMZ Cazin Catherine S J CSJ

Beilstein journal of organic chemistry 20200324

A new catalytic strategy for the one-pot synthesis of <i>N</i>-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation. ...[more]

PMID: 32273908

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