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Jaw clonus in neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome.


ABSTRACT: Jaw clonus, a fascinating, yet uncommon clinical sign, is suggestive of supranuclear lesions of the trigeminal nerve. It has previously been reported in association with amyotrophic lateral sclerosis. Hereby, we report an index case of jaw clonus in a patient of neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome with pseudobulbar palsy due to the involvement of pontine corticobulbar fibres.

SUBMITTER: Ghosh R 

PROVIDER: S-EPMC7114005 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Jaw clonus in neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome.

Ghosh Ritwik R   Roy Devlina D   Dubey Souvik S   Lahiri Durjoy D   Chatterjee Subhankar S   Finsterer Josef J  

Journal of family medicine and primary care 20200228 2


Jaw clonus, a fascinating, yet uncommon clinical sign, is suggestive of supranuclear lesions of the trigeminal nerve. It has previously been reported in association with amyotrophic lateral sclerosis. Hereby, we report an index case of jaw clonus in a patient of neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome with pseudobulbar palsy due to the involvement of pontine corticobulbar fibres. ...[more]

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