TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
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ABSTRACT:
SUBMITTER: Shen LW
PROVIDER: S-EPMC7116903 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Shen Li Wen LW Mao Hui Juan HJ Wu Yan Ling YL Tanaka Yoshimasa Y Zhang Wen W
Biochimie 20170801
Influenza virus and coronavirus epidemics or pandemics have occurred in succession worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat to human health. Here, we outline a critical role of the host cell protease TMPRSS2 in influenza virus and coronavirus infections and highlight an antiviral therapeutic strategy targeting TMPRSS2. ...[more]
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