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Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype.

ABSTRACT: The genetic diversity of 16 canine coronavirus (CCoV) samples is described. Samples were obtained from pups infected naturally living in different areas. Sequence data were obtained from the M gene and pol1a and pol1b regions. The phylogenetic relationships among these sequences and sequences published previously were determined. The canine samples segregated in two separate clusters. Samples of the first cluster were intermingled with reference strains of CCoV genotype and therefore could be assigned to this genotype. The second cluster segregated separately from CCoV and feline coronavirus genotypes and therefore these samples may represent genetic outliers. The reliability of the classification results was confirmed by repeating the phylogenetic analysis with nucleotide and amino acid sequences from multiple genomic regions.

SUBMITTER: Pratelli A

PROVIDER: S-EPMC7119488 | biostudies-literature | 2003 Feb

REPOSITORIES: biostudies-literature

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Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype.

Pratelli Annamaria A Martella Vito V Pistello Mauro M Elia Gabriella G Decaro Nicola N Buonavoglia Domenico D Camero Michele M Tempesta Maria M Buonavoglia Canio C

Journal of virological methods 20030201 2

The genetic diversity of 16 canine coronavirus (CCoV) samples is described. Samples were obtained from pups infected naturally living in different areas. Sequence data were obtained from the M gene and pol1a and pol1b regions. The phylogenetic relationships among these sequences and sequences published previously were determined. The canine samples segregated in two separate clusters. Samples of the first cluster were intermingled with reference strains of CCoV genotype and therefore could be as ...[more]

PMID: 12505636

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