Ontology highlight
ABSTRACT:
SUBMITTER: Tang NL
PROVIDER: S-EPMC7124215 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Tang Nelson Leung-Sang NL Fan Harris Pok Yin HP Chang Kwok Chiu KC Ching Jasmine Kuk Lai JK Kong Kathy Pui Shan KP Yew Wing Wai WW Kam Kai Man KM Leung Chi Chiu CC Tam Cheuk Ming CM Blackwell Jenefer J Chan Chiu Yeung CY
Clinica chimica acta; international journal of clinical chemistry 20090610 1-2
<h4>Background</h4>Previous studies showed that activation of CXCL-10 and other chemokines were prominent in many infectious diseases. These chemokines are components of innate immune response to respiratory tract pathogens. We examined the promoter variants of CXCL-10 and their role in predisposition to tuberculosis (TB).<h4>Methods</h4>The promoter 1.8 kb of CXCL-10 was sequenced in 24 healthy Chinese individuals to identify genetic polymorphisms. Three tagging SNPs in CXCL-10 promoter (-1447A ...[more]