Dataset Information

Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort.

ABSTRACT:

Background

Although physical activity has many known health benefits, its association with lung function in childhood/adolescence remains unclear. We examined the association of physical-activity trajectories between 11 and 15?years with lung function at 15?years in 2266 adolescents.

Methods

A population-based cohort of 14?305 singleton births alive at 1?year was recruited in the UK population-based Avon Longitudinal Study of Parents and Children cohort. Physical activity (counts/minute and moderate-to-vigorous physical activity) was assessed for 7?days using an accelerometer at 11, 13 and 15?years. We identified sex-specific physical-activity trajectories applying K-means for longitudinal data in children with at least two accelerometer measurements (n?=?3584). We then estimated the sex-specific associations of these trajectories with post-bronchodilation lung-function parameters using multivariable linear-regression models (n?=?2266, 45% boys).

Results

Fewer than 7% of participants met the WHO physical-activity recommendations (i.e. daily average of at least 60?minutes of moderate-to-vigorous physical activity). Boys were substantially more active than girls. In both sexes, we identified three distinct physical-activity trajectories ('low': 39.8% boys, 45.8% girls; 'moderate': 42.9% boys, 41.4% girls; and 'high' physical activity: 17.3% boys, 12.8% girls). Girls in the moderate and high physical-activity trajectories had 0.11?L [95% confidence interval (CI): 0.04-0.19] and 0.15 L (95% CI: 0.03-0.26) higher forced vital capacity than their less-active peers. No association was observed in boys.

Conclusions

Higher childhood physical activity relates to higher lung-function levels in adolescent girls. A better understanding of the mechanisms underlying this association should be pursued.

SUBMITTER: Roda C

PROVIDER: S-EPMC7124497 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Publications

Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort.

Roda Célina C Mahmoud Osama O Peralta Gabriela P GP Fuertes Elaine E Granell Raquel R Serra Ignasi I Henderson John J Jarvis Deborah D Garcia-Aymerich Judith J

International journal of epidemiology 20200201 1

<h4>Background</h4>Although physical activity has many known health benefits, its association with lung function in childhood/adolescence remains unclear. We examined the association of physical-activity trajectories between 11 and 15 years with lung function at 15 years in 2266 adolescents.<h4>Methods</h4>A population-based cohort of 14 305 singleton births alive at 1 year was recruited in the UK population-based Avon Longitudinal Study of Parents and Children cohort. Physical activity (counts/ ...[more]

PMID: 31270549

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Project description:Rationale: Body composition changes throughout life may explain the inconsistent associations reported between body mass index and lung function in children. Objectives: To assess the associations of body weight and composition trajectories from 7 to 15 years with lung function at 15 years and lung function growth between 8 and 15 years. Methods: Sex-specific body mass index, lean body mass index, and fat mass index trajectories were developed using Group-Based Trajectory Modeling on data collected at least twice between 7 and 15 years from 6,964 children (49% boys) in the UK Avon Longitudinal Study of Parents and Children birth cohort. Associations of these trajectories with post-bronchodilation lung function parameters at 15 years and with lung function growth rates from 8 to 15 years were assessed using multivariable linear regression models, stratified by sex, in a subgroup with lung function data (n = 3,575). Measurements and Main Results: For all body mass measures we identified parallel trajectories that increased with age. There was no consistent evidence of an association between the body mass index trajectories and lung function measures. Higher lean body mass index trajectories were associated with higher levels and growth rates of FVC, FEV1, and forced expiratory flow, midexpiratory phase in both sexes (e.g., boys in the highest lean body mass index trajectory had on average a 0.62 L [95% confidence interval, 0.44-0.79; P trend < 0.0001] higher FVC at 15 yr than boys in the lowest trajectory). Increasing fat mass index trajectories were associated with lower levels and growth rates of FEV1 and forced expiratory flow, midexpiratory phase only in boys and lower levels of FEV1/FVC in both sexes. Conclusions: Higher lean body mass during childhood and adolescence is consistently associated with higher lung function at 15 years in both sexes, whereas higher fat mass is associated with lower levels of only some lung function parameters.

Dataset Information

Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort.

Background

Methods

Results

Conclusions

Publications

Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort.

Similar Datasets

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