Ontology highlight
ABSTRACT:
SUBMITTER: Fan H
PROVIDER: S-EPMC7126683 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Fan Hui H Ooi Amy A Tan Yong Wah YW Wang Sifang S Fang Shouguo S Liu Ding Xiang DX Lescar Julien J
Structure (London, England : 1993) 20051201 12
The coronavirus nucleocapsid (N) protein packages viral genomic RNA into a ribonucleoprotein complex. Interactions between N proteins and RNA are thus crucial for the assembly of infectious virus particles. The 45 kDa recombinant nucleocapsid N protein of coronavirus infectious bronchitis virus (IBV) is highly sensitive to proteolysis. We obtained a stable fragment of 14.7 kDa spanning its N-terminal residues 29-160 (IBV-N29-160). Like the N-terminal RNA binding domain (SARS-N45-181) of the seve ...[more]