Ontology highlight
ABSTRACT:
SUBMITTER: Zou N
PROVIDER: S-EPMC7127571 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Zou Nianli N Xia Jing J Wang Fuyan F Duan Zhenzhen Z Miao Dan D Yan Qigui Q Cao Sanjie S Wen Xintian X Liu Ping P Huang Yong Y
Veterinary immunology and immunopathology 20150819 1-2
The spike (S) protein of the infectious bronchitis virus (IBV) plays a central role in the pathogenicity, the immune antibody production, serotype and the tissue tropism. In this study, we generate 11 monoclonal antibodies (mAbs) against S1 subunit of IBV Sczy3 strain, and two mAbs 1D5 and 6A12 were positive in indirect ELISA against both His-S1 protein and the purified whole viral antigen. MAb 6A12 and 1D5 could recognized by other 10 IBV strains (IBVs) from five different genotypes, except tha ...[more]