Overexpression of SLC6A1 associates with drug resistance and poor prognosis in prostate cancer.
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ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC7137497 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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Overexpression of SLC6A1 associates with drug resistance and poor prognosis in prostate cancer.
Chen Chaojiang C Cai Zhiduan Z Zhuo Yangjia Y Xi Ming M Lin Zhuoyuan Z Jiang Funeng F Liu Zezhen Z Wan Yueping Y Zheng Yu Y Li Jianxin J Zhou Xing X Zhu Jianguo J Zhong Weide W
BMC cancer 20200406 1
<h4>Background</h4>Solute Carrier Family 6 Member 1 (SLC6A1) has been identified as a cancer-promoting gene in various human cancers, such as clear cell renal cell carcinoma and ovarian cancer. However, its roles in prostate cancer (PCa) has not been fully elucidated. The aim of this study was to investigate the expression and clinical significance of SLC6A1 in PCa tissues and its effect on drug resistance to docetaxel in PCa.<h4>Methods</h4>Expression patterns of SLC6A1 protein in PCa tissues w ...[more]
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