Ontology highlight
ABSTRACT:
SUBMITTER: Coelho MC
PROVIDER: S-EPMC7137733 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Coêlho Marina Castro MC Queiroz Ingrid Costa IC Viana Filho José Maria Chagas JMC Aquino Sabrina Garcia de SG Persuhn Darlene Camati DC Oliveira Naila Francis Paulo de NFP
Journal of applied oral science : revista FOB 20200403
<h4>Background</h4>Genetic and epigenetic changes have been associated with periodontitis in various genes; however, little is known about genes involved in epigenetic mechanisms and in oxidative stress.<h4>Objective</h4>This study aims to investigate the association of polymorphisms C677T in MTHFR (rs1801133) and -149C→T in DNMT3B (rs2424913), as well as the methylation profiles of MTHFR, miR-9-1, miR-9-3, SOD1, and CAT with periodontitis. The association between polymorphisms and DNA methylati ...[more]