Unknown

Dataset Information

0

Investigation of cortisol dynamics in human sweat using a graphene-based wireless mHealth system.


ABSTRACT: Understanding and assessing endocrine response to stress is crucial to human performance analysis, stress-related disorder diagnosis, and mental health monitoring. Current approaches for stress monitoring are largely based on questionnaires, which could be very subjective. To avoid stress-inducing blood sampling and to realize continuous, non-invasive, and real-time stress analysis at the molecular levels, we investigate the dynamics of a stress hormone, cortisol, in human sweat using an integrated wireless sensing device. Highly sensitive, selective, and efficient cortisol sensing is enabled by a flexible sensor array that exploits the exceptional performance of laser-induced graphene for electrochemical sensing. Herein, we report the first cortisol diurnal cycle and the dynamic stress response profile constructed from human sweat. Our pilot study demonstrates a strong empirical correlation between serum and sweat cortisol, revealing exciting opportunities offered by sweat analysis toward non-invasive dynamic stress monitoring via wearable and portable sensing platforms.

SUBMITTER: Torrente-Rodriguez RM 

PROVIDER: S-EPMC7138219 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

Investigation of cortisol dynamics in human sweat using a graphene-based wireless mHealth system.

Torrente-Rodríguez Rebeca M RM   Tu Jiaobing J   Yang Yiran Y   Min Jihong J   Wang Minqiang M   Song Yu Y   Yu You Y   Xu Changhao C   Ye Cui C   IsHak Waguih William WW   Gao Wei W  

Matter 20200226 4


Understanding and assessing endocrine response to stress is crucial to human performance analysis, stress-related disorder diagnosis, and mental health monitoring. Current approaches for stress monitoring are largely based on questionnaires, which could be very subjective. To avoid stress-inducing blood sampling and to realize continuous, non-invasive, and real-time stress analysis at the molecular levels, we investigate the dynamics of a stress hormone, cortisol, in human sweat using an integra  ...[more]

Similar Datasets

| S-EPMC10221498 | biostudies-literature
| S-EPMC11207453 | biostudies-literature
| S-EPMC7527225 | biostudies-literature
| S-EPMC7161047 | biostudies-literature
| S-EPMC5645384 | biostudies-literature
| S-EPMC8948546 | biostudies-literature
| S-EPMC5376102 | biostudies-literature
| S-EPMC7193562 | biostudies-literature
| S-EPMC7351733 | biostudies-literature
| S-EPMC7490542 | biostudies-literature