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Type 1 interferons as a potential treatment against COVID-19.


ABSTRACT: Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.

SUBMITTER: Sallard E 

PROVIDER: S-EPMC7138382 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Type 1 interferons as a potential treatment against COVID-19.

Sallard Erwan E   Lescure François-Xavier FX   Yazdanpanah Yazdan Y   Mentre France F   Peiffer-Smadja Nathan N  

Antiviral research 20200407


Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19. ...[more]

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