Ontology highlight
ABSTRACT:
SUBMITTER: Lombard-Banek C
PROVIDER: S-EPMC7144572 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Lombard-Banek Camille C Schiel John E JE
Molecules (Basel, Switzerland) 20200319 6
Adoptive cell therapy is an emerging anti-cancer modality, whereby the patient's own immune cells are engineered to express T-cell receptor (TCR) or chimeric antigen receptor (CAR). CAR-T cell therapies have advanced the furthest, with recent approvals of two treatments by the Food and Drug Administration of Kymriah (trisagenlecleucel) and Yescarta (axicabtagene ciloleucel). Recent developments in proteomic analysis by mass spectrometry (MS) make this technology uniquely suited to enable the com ...[more]