Ontology highlight
ABSTRACT:
SUBMITTER: Gaspar N
PROVIDER: S-EPMC7886057 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Faculty reviews 20201126
Osteosarcoma is the most common bone cancer in adolescents and young adults, but it is a rare cancer with no improvement in patient survival in the last four decades. The main problem of this bone tumor is its evolution toward lung metastatic disease, despite the current treatment strategy (chemotherapy and surgery). To further improve survival, there is a strong need for new therapies that control osteosarcoma cells with metastatic potential and their favoring tumor microenvironment (ME) from t ...[more]