Ontology highlight
ABSTRACT:
SUBMITTER: Hoeijmakers WAM
PROVIDER: S-EPMC7145593 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Hoeijmakers Wieteke Anna Maria WAM Miao Jun J Schmidt Sabine S Toenhake Christa Geeke CG Shrestha Sony S Venhuizen Jeron J Henderson Rob R Birnbaum Jakob J Ghidelli-Disse Sonja S Drewes Gerard G Cui Liwang L Stunnenberg Hendrik Gerard HG Spielmann Tobias T Bártfai Richárd R
Nucleic acids research 20191201 22
Epigenetic regulatory mechanisms are central to the development and survival of all eukaryotic organisms. These mechanisms critically depend on the marking of chromatin domains with distinctive histone tail modifications (PTMs) and their recognition by effector protein complexes. Here we used quantitative proteomic approaches to unveil interactions between PTMs and associated reader protein complexes of Plasmodium falciparum, a unicellular parasite causing malaria. Histone peptide pull-downs wit ...[more]