The Role of Secretory Pathways in Candida albicans Pathogenesis.
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ABSTRACT:
SUBMITTER: Rollenhagen C
PROVIDER: S-EPMC7151058 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
The Role of Secretory Pathways in <i>Candida albicans</i> Pathogenesis.
Rollenhagen Christiane C Mamtani Sahil S Ma Dakota D Dixit Reva R Eszterhas Susan S Lee Samuel A SA
Journal of fungi (Basel, Switzerland) 20200224 1
<i>Candida albicans</i> is a fungus that is a commensal organism and a member of the normal human microbiota. It has the ability to transition into an opportunistic invasive pathogen. Attributes that support pathogenesis include secretion of virulence-associated proteins, hyphal formation, and biofilm formation. These processes are supported by secretion, as defined in the broad context of membrane trafficking. In this review, we examine the role of secretory pathways in <i>Candida</i> virulence ...[more]
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