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Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery.

ABSTRACT: Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies.

SUBMITTER: Pinelli F

PROVIDER: S-EPMC7151136 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery.

Pinelli Filippo F Perale Giuseppe G Rossi Filippo F

Gels (Basel, Switzerland) 20200204 1

Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a fin ...[more]

PMID: 32033057

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