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Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration.

ABSTRACT: The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal muscle, from embryonic to postnatal development. Furthermore, complementary studies have recently demonstrated that specific components of the pathway are required for efficient muscle regeneration.

SUBMITTER: Borok MJ

PROVIDER: S-EPMC7151139 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration.

Borok Matthew J MJ Mademtzoglou Despoina D Relaix Frederic F

Journal of developmental biology 20200211 1

The bone morphogenetic protein (BMP) pathway is best known for its role in promoting bone formation, however it has been shown to play important roles in both development and regeneration of many different tissues. Recent work has shown that the BMP proteins have a number of functions in skeletal muscle, from embryonic to postnatal development. Furthermore, complementary studies have recently demonstrated that specific components of the pathway are required for efficient muscle regeneration. ...[more]

PMID: 32053985

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