The clinical course and its correlated immune status in COVID-19 pneumonia.

ABSTRACT:

Objectives

To explore the clinical course and its dynamic features of immune status in COVID-19 patients and find predictors correlated with severity and prognosis of COVID-19.

Methods

The electronic medical records of 204 patients with COVID-19 pneumonia confirmed by nucleic acid testing were retrospectively collected and analyzed.

Results

All patients were divided into severe (69) and non-severe group (135). Lymphocyte subsets count, including CD3⁺ T cell, CD4⁺ T cell, CD8⁺ T cell, B cell (CD19⁺) and NK cell (CD16⁺ 56⁺), were significantly lower in severe group (P＜0.001). The dynamic levels of T lymphocyte in severe group were significantly lower from disease onset, but in the improved subgroup the va

SUBMITTER: He R 

PROVIDER: S-EPMC7152870 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature