Ontology highlight
ABSTRACT:
SUBMITTER: Husain SM
PROVIDER: S-EPMC7154522 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chembiochem : a European journal of chemical biology 20191209 6
Partially reduced aromatic polyketides are bioactive secondary metabolites or intermediates in the biosynthesis of deoxygenated aromatics. For the antibiotic GTRI-02 (mensalone) in different Streptomyces spp., biosynthesis involving the reduction of a fully aromatized acetyltrihydroxynaphthalene by a naphthol reductase has been proposed and shown in vitro with a fungal enzyme. However, more recently, GTRI-02 has been identified as a product of the ActIII biosynthetic gene cluster from Streptomyc ...[more]