Ontology highlight
ABSTRACT:
SUBMITTER: Kahn J
PROVIDER: S-EPMC7154701 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Kahn Judith J Pregartner Gudrun G Schemmer Peter P
Transplant international : official journal of the European Society for Organ Transplantation 20200212 4
While rejection prevention with innovator tacrolimus (Tac) is one of the key factors for long-lasting graft function, the use of generic Tac is still under debate. Thus, we performed a systematic review and meta-analysis to provide an overview on the current body of evidence for the effect of generic Tac in adult liver (LT) and kidney transplantation (KT) with focus on both biopsy-proven acute rejection (BPAR) and bioequivalence. A systematic literature search for trials comparing generic versus ...[more]