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Quantitative Analysis of Salivary Oral Bacteria Associated with Severe Early Childhood Caries and Construction of Caries Assessment Model.

ABSTRACT: To construct a saliva-based caries risk assessment model, saliva samples from 176 severe early childhood caries (S-ECC) children and 178 healthy (H) children were screened by real-time PCR-based quantification of the selected species, including Streptococcus mutans, Prevotella pallens, Prevotella denticola and Lactobacillus fermentum. Host factors including caries status, dmft indices, age, gender, and geographic origin were assessed in their influence on abundance of the targeted species, which revealed host caries status as the dominant factor, followed by dmft indices (both P?

SUBMITTER: Zhang L 

PROVIDER: S-EPMC7156402 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Quantitative Analysis of Salivary Oral Bacteria Associated with Severe Early Childhood Caries and Construction of Caries Assessment Model.

Zhang Lijuan L   Sun Tongzheng T   Zhu Pengfei P   Sun Zheng Z   Li Shanshan S   Li Fan F   Zhang Ying Y   Tan Kaixuan K   Lu Jie J   Yuan Rongtao R   Chen Zhenggang Z   Guo Dawei D   Guo Qingyuan Q   Teng Fei F   Yang Fang F  

Scientific reports 20200414 1

To construct a saliva-based caries risk assessment model, saliva samples from 176 severe early childhood caries (S-ECC) children and 178 healthy (H) children were screened by real-time PCR-based quantification of the selected species, including Streptococcus mutans, Prevotella pallens, Prevotella denticola and Lactobacillus fermentum. Host factors including caries status, dmft indices, age, gender, and geographic origin were assessed in their influence on abundance of the targeted species, which  ...[more]

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