Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC7159506 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Chen Jianwen J Pan Kaiyuan K Chen Zhen Z Li Yunsheng Y Ding Biao B Han Chunyang C Cao Zubing Z Bao Wenbin W Zhang Yunhai Y
Animal science journal = Nihon chikusan Gakkaiho 20190108 3
Porcine viral diarrhea is an acute and highly contagious enteric disease in pigs which causes huge economic losses in pig industry worldwide. Transmissible gastroenteritis virus (TGEV) is main pathogens responsible for piglets viral diarrhea. Knockout the host cellular surface receptor for TGEV may be an effective way to accelerate the breeding of resistant pigs. In this study, we applied site-specific editing pAPN which is effective in swine testis (ST) cells. Site-specific editing of pAPN redu ...[more]