Ontology highlight
ABSTRACT:
SUBMITTER: Ravula T
PROVIDER: S-EPMC7161179 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20190911 42
Experimentally measured residual dipolar couplings (RDCs) are highly valuable for atomic-resolution structural and dynamic studies of molecular systems ranging from small molecules to large proteins by solution NMR spectroscopy. Here we demonstrate the first use of magnetic-alignment behavior of lyotropic liquid-crystalline polymer macro-nanodiscs (>20 nm in diameter) as a novel alignment medium for the measurement of RDCs using high-resolution NMR. The easy preparation of macro-nanodiscs, their ...[more]