Ontology highlight
ABSTRACT:
SUBMITTER: Xiang H
PROVIDER: S-EPMC7161711 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Xiang Honggang H Zhang Jifa J Lin Congcong C Zhang Lan L Liu Bo B Liu Bo B Ouyang Liang L
Acta pharmaceutica Sinica. B 20191018 4
Autophagy, defined as a scavenging process of protein aggregates and damaged organelles mediated by lysosomes, plays a significant role in the quality control of macromolecules and organelles. Since protein kinases are integral to the autophagy process, it is critically important to understand the role of kinases in autophagic regulation. At present, intervention of autophagic processes by small-molecule modulators targeting specific kinases has becoming a reasonable and prevalent strategy for t ...[more]