Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Berna AJ
PROVIDER: S-EPMC7166730 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Pérez-Berná A J AJ Veiga A S AS Castanho M A R B MA Villalaín J J
Journal of viral hepatitis 20071221 5
We have analysed and identified different membrane-active regions of the Hepatitis C virus (HCV) core protein by observing the effect of 18-mer core-derived peptide libraries from two HCV strains on the integrity of different membrane model systems. In addition, we have studied the secondary structure of specific membrane-interacting peptides from the HCV core protein, both in aqueous solution and in the presence of model membrane systems. Our results show that the HCV core protein region compri ...[more]