Ontology highlight
ABSTRACT:
SUBMITTER: Yang Q
PROVIDER: S-EPMC7167459 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20200330 9
Tissue-resident memory T cells (TRMs) have a key role in mediating the host defense against tuberculosis (TB) in mice, but their human counterparts have not been well characterized. In this article, we recruited patients with TB and determined TRM frequency, trafficking, activation marker expression, and cytokine production by flow or mass cytometry at different infection sites, including peripheral blood, pleural fluid, bronchoalveolar lavage fluid, and lung. We found a high frequency of TRMs a ...[more]