Ontology highlight
ABSTRACT:
SUBMITTER: Sojka DK
PROVIDER: S-EPMC6552671 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20181001 9
NK cells accumulate in adult murine and human uteri during decidualization induced physiologically, pathologically, or experimentally. Adoptive transfer studies indicate that uterine NK (uNK) cells arise from circulating progenitors. However, virgin uteri contain few circulating NK1.1<sup>+</sup>CD49a<sup>-</sup> conventional NK cells, whereas NK1.1<sup>+</sup>CD49a<sup>+</sup> tissue-resident NK (trNK) cells are abundant. In this study, we employed a novel, immune-competent NK cell-specific rep ...[more]