Ontology highlight
ABSTRACT:
SUBMITTER: Jiang Y
PROVIDER: S-EPMC7170847 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Jiang Yuyan Y Zhao Xuhui X Huang Jiaguo J Li Jingchao J Upputuri Paul Kumar PK Sun He H Han Xiao X Pramanik Manojit M Miao Yansong Y Duan Hongwei H Pu Kanyi K Zhang Ruiping R
Nature communications 20200420 1
Despite its growing promise in cancer treatment, ferrotherapy has low therapeutic efficacy due to compromised Fenton catalytic efficiency in tumor milieu. We herein report a hybrid semiconducting nanozyme (HSN) with high photothermal conversion efficiency for photoacoustic (PA) imaging-guided second near-infrared photothermal ferrotherapy. HSN comprises an amphiphilic semiconducting polymer as photothermal converter, PA emitter and iron-chelating Fenton catalyst. Upon photoirradiation, HSN gener ...[more]