Ontology highlight
ABSTRACT:
SUBMITTER: Flasch M
PROVIDER: S-EPMC7171601 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
ACS chemical biology 20200325 4
Xenobiotics are ubiquitous in the environment and modified in the human body by phase I and II metabolism. Liquid chromatography coupled to high resolution mass spectrometry is a powerful tool to investigate these biotransformation products. We present a workflow based on stable isotope-assisted metabolomics and the bioinformatics tool MetExtract II for deciphering xenobiotic metabolites produced by human cells. Its potential was demonstrated by the investigation of the metabolism of deoxynivale ...[more]