Ontology highlight
ABSTRACT:
SUBMITTER: Bauer L
PROVIDER: S-EPMC7172203 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Bauer Lisa L Lyoo Heyrhyoung H van der Schaar Hilde M HM Strating Jeroen Rpm JR van Kuppeveld Frank Jm FJ
Current opinion in virology 20170412
Enteroviruses (e.g., poliovirus, enterovirus-A71, coxsackievirus, enterovirus-D68, rhinovirus) include many human pathogens causative of various mild and more severe diseases, especially in young children. Unfortunately, antiviral drugs to treat enterovirus infections have not been approved yet. Over the past decades, several direct-acting inhibitors have been developed, including capsid binders, which block virus entry, and inhibitors of viral enzymes required for genome replication. Capsid bin ...[more]