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ABSTRACT:
SUBMITTER: Sivakumaran K
PROVIDER: S-EPMC7172556 | biostudies-literature | 1999 Dec
REPOSITORIES: biostudies-literature
Sivakumaran K K Kim C H CH Tayon R R Kao C C CC
Journal of molecular biology 19991201 3
Viral RNA replication provides a useful system to study the structure and function of RNAs and the mechanism of RNA synthesis from RNA templates. Previously we demonstrated that a 27 nt RNA from brome mosaic virus (BMV) can direct correct initiation of genomic plus-strand RNA synthesis by the BMV replicase. In this study, using biochemical, nuclear magnetic resonance, and thermodynamic analyses, we determined that the secondary structure of this 27 nt RNA can be significantly altered and retain ...[more]