Ontology highlight
ABSTRACT:
SUBMITTER: Balasuriya UB
PROVIDER: S-EPMC7172799 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Balasuriya Udeni B R UB Zhang Jianqiang J Go Yun Young YY MacLachlan N James NJ
Virology 20140607
The advent of recombinant DNA technology, development of infectious cDNA clones of RNA viruses, and reverse genetic technologies have revolutionized how viruses are studied. Genetic manipulation of full-length cDNA clones has become an especially important and widely used tool to study the biology, pathogenesis, and virulence determinants of both positive and negative stranded RNA viruses. The first full-length infectious cDNA clone of equine arteritis virus (EAV) was developed in 1996 and was a ...[more]