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May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?


ABSTRACT: COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females. Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly used for BPH treatment, may be one of the factors contributing to poorer prognosis in males.

SUBMITTER: Adamowicz J 

PROVIDER: S-EPMC7175887 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?

Adamowicz Jan J   Juszczak Kajetan K   Drewa Tomasz T  

Medical hypotheses 20200422


COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females. Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly used for BPH treatment, may be one of the factors contributing to poorer prognosis in males. ...[more]

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