Ontology highlight
ABSTRACT:
SUBMITTER: Gouveia C
PROVIDER: S-EPMC7177533 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Gouveia Chantel C Huyser Carin C Egli Dieter D Pepper Michael S MS
International journal of molecular sciences 20200327 7
Somatic cell nuclear transfer (SCNT) has been an area of interest in the field of stem cell research and regenerative medicine for the past 20 years. The main biological goal of SCNT is to reverse the differentiated state of a somatic cell, for the purpose of creating blastocysts from which embryonic stem cells (ESCs) can be derived for therapeutic cloning, or for the purpose of reproductive cloning. However, the consensus is that the low efficiency in creating normal viable offspring in animals ...[more]