Ontology highlight
ABSTRACT:
SUBMITTER: Liang Y
PROVIDER: S-EPMC7179173 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Liang Yongxi Y Tang Mei-Lin ML Huo Zhipeng Z Zhang Chenchen C Sun Xun X
Molecules (Basel, Switzerland) 20200304 5
An efficient approach to obtain functionalized rhodanines was developed through a base-assisted one-pot coupling and continuous cyclization of a primary amine, carbon disulfide, and methyl (2-chloroacetyl)carbamate. This conversion tolerates a broad range of functional groups and can be used to scale the preparation of <i>N</i>-substituted rhodanines in excellent yields. ...[more]