Dataset Information
Concise one-pot preparation of unique bis-pyrrolidinone tetrazoles.
Ontology highlight
ABSTRACT:
SUBMITTER: Gunawan S
PROVIDER: S-EPMC3299871 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Concise one-pot preparation of unique bis-pyrrolidinone tetrazoles.
ACS combinatorial science 20120215 3
A one-pot, two-step synthesis of bis-pyrrolidinone tetrazoles has been established via the Ugi-Azide reaction using methyl levulinate, primary amines, isocyanides and azidotrimethylsilane with subsequent acid treatment to catalyze the lactam formation. The efficiency of the protocol was established followed by a successful transition to library production in four 24-well plates. ...[more]
