Oscillating steady-state imaging (OSSI): A novel method for functional MRI.

ABSTRACT:

Purpose

Signal-to-noise ratio (SNR) is crucial for high-resolution fMRI; however, current methods for SNR improvement are limited. A new approach, called oscillating steady-state imaging (OSSI), produces a signal that is large and T2∗ -weighted, and is demonstrated to produce improved SNR compared to gradient echo (GRE) imaging with matched effective TE and spatial-temporal acquisition characteristics for high-resolution fMRI.

Methods

Quadratic phase sequences were combined with balanced gradients to produce a large, oscillating steady-state signal. The quadratic phase progression was periodic over short intervals such as 10 TRs, inducing a frequency-dependent phase dispersal. Images over one period were combined to produce a single image with effectively T2∗ -weighting. The

SUBMITTER: Guo S 

PROVIDER: S-EPMC7180136 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature