Ontology highlight
ABSTRACT:
SUBMITTER: Liang L
PROVIDER: S-EPMC7180821 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Liang Li L Wang Zhen-Jie ZJ Ye Guang G Tang Xue-You XY Zhang Yuan-Yuan YY Kong Jing-Xia JX Du Hua-Hua HH
Molecules (Basel, Switzerland) 20200325 7
Lactoferrin (Lf) is a conserved iron-binding glycoprotein with antimicrobial activity, which is present in secretions that recover mucosal sites regarded as portals of invaded pathogens. Although numerous studies have focused on exogenous Lf, little is known about its expression of endogenous Lf upon bacterial infection. In this study, we investigated the distribution of Lf in mice intestine during <i>Escherichia coli (E. coli)</i> K88 infection. PCR and immunohistology staining showed that mRNA ...[more]