Ontology highlight
ABSTRACT:
SUBMITTER: Andreani J
PROVIDER: S-EPMC7182748 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Microbial pathogenesis 20200425
Human coronaviruses SARS-CoV-2 appeared at the end of 2019 and led to a pandemic with high morbidity and mortality. As there are currently no effective drugs targeting this virus, drug repurposing represents a short-term strategy to treat millions of infected patients at low costs. Hydroxychloroquine showed an antiviral effect in vitro. In vivo it showed efficacy, especially when combined with azithromycin in a preliminary clinical trial. Here we demonstrate that the combination of hydroxychloro ...[more]